Semaglutide: Weight Loss Miracle?

What is Semaglutide?

Semaglutide is a glucagon-like peptide (GLP-1) analog FDA approved in 2017. Studies have demonstrated that Semaglutide reduced appetite, improved control of eating, and reduced food cravings in addition to improving sugar metabolism - thus subsequently making fat metabolism more efficient. The greatest weight loss benefits were observed when Semaglutide is used in combination with lifestyle changes, such as improved diet and consistent exercise.

How does Semaglutide work?

GLP-1 is a hormone produced in the small intestine that stimulates insulin secretion and inhibits glucagon secretion, thereby improving sugar metabolism.

Other benefits include:

• Neuroprotective
• Improved Fertility
• Treatment of PCOS
• Liver protective
• Cardiovascular Benefits

How should Semaglutide be used?

Semaglutide is a subcutaneous, once weekly injection. Dosage schedule may change for maintainance of goal weight. This medication is approved for long term use. This medication is generally well-tolerated and can be dosed continuously without breaking treatment with no diminishing effects.

What are the Side effects and contraindications?

The most commonly reported side effects include nausea, vomiting, diarrhea, stomach pain, and constipation. The risk of serious side effects increases in patients with hypoglycemia, kidney problems, and risk of allergic reactions.

This medication is not an insulin and should not be used if:

• You have type 1 diabetes or if you develop diabetic ketoacidosis.
• Contraindicated if you have a family history of MEN type II or thyromedulary cancers.